Triple X syndrome

A chromosomal abnormality characterized by the presence of an additional X chromosome in each of a female's cells. Affected individuals may be taller than average but they typically do not have any unusual physical features and most experience normal sexual development and are fertile. Triple X syndrome is associated with an increased risk of LEARNING DISORDERS and delayed development of speech and language skills. Delayed development of motor skills, HYPOTONIA, and behavioral and emotional disturbances may also occur. SEIZURES or kidney abnormalities occur in about 10 percent of cases.

Also Known As:

47,XXX syndrome; 47,Xxx; Super female; Triple-X chromosome syndrome; Triple-X female; Triplo X syndrome; Trisomy X; XXX syndrome

Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10023
  - Chromosome Aberrations: 11361
    - Aneuploidy: 8932
      - Trisomy: 1642
        Triple X syndrome: 96
    - Chromosome Duplication: 167
      - Trisomy: 1642
        Triple X syndrome: 96
    - Sex Chromosome Aberrations: 73
      - Triple X syndrome: 96
Genetic Phenomena
- Genetic Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        6-12 and X Human Chromosomes
        X Human Chromosomes
        Triple X syndrome: 96
    - Sex Chromosomes
      - X Chromosome
        X Human Chromosomes
        Triple X syndrome: 96
- Genetic Variation
  - Mutation
    - Chromosome Aberrations: 11361
      - Aneuploidy: 8932
        Trisomy: 1642
        Triple X syndrome: 96
      - Chromosome Duplication: 167
        Trisomy: 1642
        Triple X syndrome: 96
      - Sex Chromosome Aberrations: 73
        Triple X syndrome: 96
- Ploidies
  - Aneuploidy: 8932
    - Trisomy: 1642
      - Triple X syndrome: 96
Cells
- Cellular Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        6-12 and X Human Chromosomes
        X Human Chromosomes
        Triple X syndrome: 96
    - Sex Chromosomes
      - X Chromosome
        X Human Chromosomes
        Triple X syndrome: 96
Urogenital Diseases: 126
- Urogenital Abnormalities: 76
  - Disorders of Sex Development: 730
    - Sex Chromosome Disorders of Sex Development: 3
      - Triple X syndrome: 96
- Female Urogenital Diseases and Pregnancy Complications
  - Female Urogenital Diseases
    - Urogenital Abnormalities: 76
      - Disorders of Sex Development: 730
        Sex Chromosome Disorders of Sex Development: 3
        Triple X syndrome: 96
- Male Urogenital Diseases
  - Urogenital Abnormalities: 76
    - Disorders of Sex Development: 730
      - Sex Chromosome Disorders of Sex Development: 3
        Triple X syndrome: 96
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Chromosome Disorders: 136
    - Sex Chromosome Disorders: 5
      - Sex Chromosome Disorders of Sex Development: 3
        Triple X syndrome: 96
  - Urogenital Abnormalities: 76
    - Disorders of Sex Development: 730
      - Sex Chromosome Disorders of Sex Development: 3
        Triple X syndrome: 96
- Inborn Genetic Diseases: 11939
  - Chromosome Disorders: 136
    - Sex Chromosome Disorders: 5
      - Sex Chromosome Disorders of Sex Development: 3
        Triple X syndrome: 96
Endocrine System Diseases: 968
- Gonadal Disorders: 30
  - Disorders of Sex Development: 730
    - Sex Chromosome Disorders of Sex Development: 3
      - Triple X syndrome: 96

Jonathan D Blumenthal Selected Research

Jonathan D Blumenthal Research Topics

Disease

Drug/Important Bio-Agent (IBA)